College Football Week 4 Expert Predictions, Odds: Notre Dame Battles Wisconsin In Chicago, Texas A&M Meets Arkansas

Given the history of this series, USC-Notre Dame is still a notable matchup. Except in 2021, the marquee has a few bulbs out. The lettering is slightly crooked, specifically where it would say ‘Trojans.’ While Notre Dame slotted in at 13 in the latest AP poll and remained in the hunt for New Year’s Six consideration, Southern California is coming off its bye week at 3-3 on the season, 2-2 under interim coach Donte Williams.

The Trojans have been reasonably predictable. When they get stops, they’re competitive. When they don’t, look away. USC has allowed 465.3 yards and 43 points per game in three losses. The Fighting Irish have won three in a row over USC and could potentially jump-start their offense against a leaky Trojans defense. Notre Dame opened as seven-point favorites.

This one will be under the lights in South Bend with a 7:30 p.m. ET kickoff on NBC.

Odds, Over/Under, Moneyline

TeamSpreadTotalMoneyline
USC+210
Notre Dame-758.5-275

Odds updated at 4:05 p.m. ET on Wednesday. Click here for live odds.

img src="https://cdn.theathletic.com/app/uploads/2021/09/30155303/Betting_Inline_CTA_2-200.png" alt=""">

USC-Notre Dame storylines

Notre Dame-USC rivalry renewed: Which weaknesses will loom largest? Beat writer breakdown

Notre Dame at midseason: This ‘bridge season’ is going better, worse and wilder than expected, all at once

USC at midseason: What can be salvaged down the stretch from the fallout of Clay Helton’s firing?

USC football recruiting news: Devin Brown’s growing list of options, Domani Jackson’s commitment and more

Expert picks against the spread

Picks made at Notre Dame -6.5.

Pick
Dan Santaromita Notre Dame
Jason Starrett Notre Dame
Chris Vannini Notre Dame
Ari Wasserman USC

(Photo of Kedon Slovis: Brian Rothmuller / Icon Sportswire via Getty Images; The Athletic may receive an affiliate commission if you open an account with BetMGM through links contained in the above article.)

Source : https://theathletic.com/2900670/2021/10/20/usc-at-notre-dame-spread-expert-predictions-odds-betting-trends-trojans-irish-rivalry-adds-another-chapter-from-south-bend/

1275
USC at Notre Dame spread, expert predictions, odds, betting trends: Trojans-Irish rivalry adds another chapter from South Bend

Source:The Athletic

USC at Notre Dame spread, expert predictions, odds, betting trends: Trojans-Irish rivalry adds another chapter from South Bend

College football spreads: Updated Vegas odds for Week 4s biggest games

Source:247 Sports

College football spreads: Updated Vegas odds for Week 4s biggest games

College football predictions Week 4: Big SEC games highlight slate

Source:247 Sports

College football predictions Week 4: Big SEC games highlight slate

Week 5 college football picks: Cincinnati at Notre Dame, ASU at UCLA and more

Source:Yahoo! Sports

Week 5 college football picks: Cincinnati at Notre Dame, ASU at UCLA and more

College football schedule, games 2021: What to watch in Week 4, TV channels, Saturday kickoff times

Source:CBSSports.com

College football schedule, games 2021: What to watch in Week 4, TV channels, Saturday kickoff times

College Football Week 5: Stack The Cash, win big with FOX Super 6

Source:Fox Sports

College Football Week 5: Stack The Cash, win big with FOX Super 6